L-Glutamine Benefits

L-glutamine is another one of those buzzwords in the fitness industry and seems to be highly acclaimed for its ability strip fat and build lean muscle. In this post we will take a deeper look into L-glutamine benefits and side effects so you can decide for yourself whether this supplement is right for you.



L-glutamine is an amino acid needed in the body for the biosynthesis of proteins. It is the most abundant amino acid in our bloodstream, and more than 61% of our skeletal muscle is made up of it,  and 90% of our body’s l-glutamine is synthesised in our skeletal muscle.

However, there can be a problem sometimes with glutamine synthesis in certain individuals, such as the sick or premature babies, making it much herder for them to produce their own. In such cases as the l-glutamine then becomes an essential amino acid.



big bicep muscles

Glutamine is crucial in our bodies, it is essential for providing fuel to our cells in order to make other amino acids, and to produce glucose. It is especially needed in times of stress, both physical and mental, as it will be burnt up very quickly under these conditions. This is one of the reasons why l-glutamine is so popular in the fitness industry, because physical training puts constant stress on the muscles and immune system.

When intensely training, levels of glutamine are vastly depleted, which decreases overall strength, stamina, and recovery time. In fact, after an intense session it can take up to 6 days for levels to return to what they should be, which isn’t good if you like to train at least 3 to 4 times a week.


L- glutamine for Muscle Repair and Growth:-

Studies show that glutamine supplementation can improve the metabolism of protein, meaning it can also be used for muscle repair and growth – which is yet another reason why it is so popular with those on an intense training program, or lifting heavy weights.



L-glutamine is definitely up there as a fat burner because it helps counteract the storage of fat and so helps to regulate weight, it also reduces cravings for sugar and alcohol which are up there with the worst belly fat offenders. During intense exercise l-glutamine also helps with the process of outing fat WITHOUT losing vital muscle mass – which is very easily done when exercising, and is often also a side effect of weight loss.


The Plant Based Diet:-

All this can be negated with a few simple strategies and a proper eating plan, which is why I recommend an alkaline plant based diet and obtaining the bulk of your proteins from plant foods such as quinoa, nuts, seeds, pulses, and plant based protein powders. Eating more alkaline foods will help temper any chronic inflammation in your body, and will also quicken your recovery time after exercise. This was th3 first and most prevalent thing I noticed when I startedfocusing on plant foods.



L-carnitine is another amino acid I have been looking into recently, which also has an impressive profile for fat burning during exercise, among its many other benefits. The reason I mention it is because it is often used alongside l-glutamine for even more enhanced fat burning and muscle building effects. 

There are many other ways you can build muscle whilst burning fat and you should incorporate some of them into your daily regime, and NOT just rely on one thing. You will always get the best fat burning results by hitting it from many different angles that include diet, exercise, and sometimes added supplements.



An intense workout (especially body building) depletes your stores of glutamine, and as glutamine plays such an important role in the immune system this can leave you more susceptible to catching bugs and other illnesse’s. Who’s noticed getting sick after they know they have overdone it in the gym or out running? I know I have – pushing your body too far, too soon can really have a knock on effect on the immune system, so it is vital to keep it strong and healthy with a supplement such as l-glutamine.

This in itself could be a good reason to use l-glutamine, especially if you do like to push yourself during training, and of course pushing yourself gradually IS certainly something that you need to do in order to get stronger, fitter and leaner. It’s just a good idea not to take this too far, too quickly, if you want to keep your immune system strong.


Other Uses For L-Glutamine

L-glutamine is also used in the medical world for many other reasons, one being as a protection for the immune system in patients undergoing cancer treatment, such as radiotherapy. It is also used after bone marrow transplants and bowel surgery to improve recovery, prevent infection, and increase well-being.



L-glutamine can also be used in the treatment of various mental illnesses and disorders, such as depression, anxiety, insomnia and ADHD. It has a stabilising effect, and unlike many other medications is able to cross the blood brain barrier. This means it may stimulate GABA: a neurotransmitter that sends chemical messages through the nervous system and brain, and changing these messages may result in relief from some of these disorders.

Although more research needs to be done in this field, as with many natural mood disorder treatments, sometimes it can be a case of trial and error to find what works for you specifically.



Another very popular use for l-glutamine is for healing the cells in the lining of the gut that may have been damaged by LGS (leaky gut syndrome). LGS can often be a side effect of IBS (irritable bowel syndrome).

The inflammation that goes with this disorder can damage the intestinal lining. Experts are not sure whether IBS causes LGS or vice versa, and it is a field that still needs much more research; there is no real cure as of yet, not medically at least.


Other Issues Caused by leaky Gut:

inflamed bowel and stomach pain

Having a leaky gut can cause so many issues in the body that it is fast becoming a leading chronic health issue. Some of the problems caused are auto immune diseases, skin problems, allergies, asthma, autism, arthritis, SIRS and type 1 diabetes.

Symptoms of leaky gut include: inflammatory diseases, food sensitivities, auto immune diseases, malabsorbption of key nutrients such as Vitamin B12, magnesium and other enzymes, and mood disorders, including autism.

This is a long list of which I haven’t gone into much detail as it requires much more in depth study, but bottom line – it seems that leaky gut syndrome may be a root cause of many problems and certainly requires deeper investigation if you feel you may be suffering from it.


Healing A Leaky Gut:

sauerkraut contains healthy, gut friendly bacteria

While l-glutamine may help to repair a leaky gut, this is only a small part of the healing process and there are other steps that involve the cutting out of certain foods. These include foods such as sugar, grains, non organic animal products, and alcohol, then adding in healing foods such as live enzymes, and probiotic foods like sauerkraut.

It is after this that you would begin the repair process and this is where l-glutamane would come in with its abilities to heal stomach lining. You would then need to repopulate the guts good bacteria with a good quality probiotics. This process is called the 4 R System.

All this is a process that needs to be done either under the supervision of a professional, or with proper understanding of it.

If you feel like having a go at making your own sauerkraut to help heal your leaky gut then please check out this video below.


  • Helps protein synthesis
  • Helps strip fat and promotes lean muscle growth
  • Is a great immune booster
  • May help with mental disorders such as depression and anxiety
  • May help combat insomnia
  • Has many medical uses (of which I would suggest you consult your doctor about before use)



As with all supplements they are most definitely NOT all created equal. Some are filled with preservatives, chemicals, fillers, and many more nasties, and if it is something you need to take long term then just think of how detrimental it would be to keep filling your body with rubbish. Many of these will have names that are unrecognisable so you don’t really know what you are putting in your body, or the potential side effects of this added junk.

Make sure to buy from reputable companies and brands. Here I have sourced out what I think is good quality l-glutamine

Trusted Brand – Amazon: SOLGAR 500mg L- GLUTAMINE CAPSULES


Possible Side Effects:

It is important to ALWAYS read labels. Side effects are pretty rare and usually only occur when too much is taken, but are generally mild and may include stomach aches and cramps, nausea, vomiting, mild skin rash, dizziness, itching and headache. If these occur then you should stop taking the supplement and consult your doctor who may suggest a different dosage, or to stop completely.



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Stefanie Taylor

I have studied nutrition for many years, and have since discovered that a plant based diet has been the most beneficial to my health and body. I have more energy and zest for life than I have ever had and this website is dedicated to helping others who wish to know more, and start out on this lifestyle.


Matts Mom · 06/11/2017 at 4:01 pm

This sounds like something that I need! Mostly for insomnia. I have been having a hard time sleeping at night due to a prescription that I take, rendering me so tired during the day. I am going to head on over to your link and try this out. Heck the other benefits are not bad either. Boosting my immune system would be great as well.

    Stefanie Taylor · 06/11/2017 at 6:29 pm

    Hi Matts Mom, thanks for reading and yes I know exactly what it’s like not to sleep as I suffered insomnia for years until I got into health and fitness. Now it has greatly improved thank god. Yes, I recommend you give L- Glutamine a go to see how it works for you. Anything is worth a shot as what works for one may not always work for another as we are all different. Good luck and please do let me know how you get on.

    Another few tip for insomnia that worked for me is never drink caffeine after 3pm (it really does make a difference) and also, you may benefit from some magnesium at night as this helps relax muscles. Just make sure it’s a good brand! Other sleep herbs include Valerian, passionflower, vervain, lemon balm, lemon verbena an chamomile. You can often buy these in tea form or if you want stronger then supplements. Hope this helps and please keep me informed as I would like to know how you are getting on.

Jose · 06/11/2017 at 4:06 pm

As someone who’s trying to shed a few extra pounds and is trying to get more into health and fitness, I found this article very helpful and informative. I’ll definitely be checking out those l-glutamine capsules!

    Stefanie Taylor · 06/11/2017 at 6:37 pm

    Hi Jose, glad this article was helpful to you and yes you should give them a try if you are in a serious exercise program, I actually would suggest taking the amino acid L- Carnitine with them as I said in the post for maximum benefits. And if you are only going to take one I would actually recommend you take just the l- Carnitine as it will work better to cut fat. Read my post on L-Carnitine here and decide for yourself.

Keith Hightower · 06/11/2017 at 5:17 pm

Enjoyed you post! I thought it was very clear–the benefits of L-Glutamine, and when it might be beneficial to supplement with it. I liked that you pointed out where more research was needed to determine the benefits in certain situations.

    Stefanie Taylor · 06/11/2017 at 6:32 pm

    Hi Keith, thanks for enjoying the article, yes I always like to be thorough in my posts and tell all sides of the story. Too many people are trying to make a quick buck and up selling products by being totally biased. Really annoying, I only want to promote products that I think can genuinely improve peoples lives.

Jaden Ho · 08/11/2017 at 1:58 pm

Such a splendid work you have done here. I had no idea L- Glutamine could helps with mental disorders, and your information about building muscle and fat loss because of L – Glutamine was very interesting. I need some L- glutamines to help me lose my belly fat. Thank you for your information.


    Stefanie Taylor · 08/11/2017 at 5:03 pm

    Hi Jayden, thanks for reading and I glad you found the article informative. Yes L-Glutamine seems to be a great supplement for many things but remember that for est results, as with most things, you should always combine with a good fitness plan/regime and a healthy diet. It is never usually just one thing that will help with chronic issues, rather a culmination of different thing. You have to hit it from all angles so to speak. Good luck.

Melissa · 08/11/2017 at 5:13 pm

That is amazing information. I have never heard about L- Glutamine but you have definitely peaked my interest. One reason being I have insomnia which in my case can be dangerous because I can have seizures while I sleep so getting rest is essential. The other reason is I have IBS and I never heard of the leaky gut so that worries me and is something I will discuss with my doctor because I have been having a lot of difficulties lately. Thanks for this article it came at the perfect time.

    Stefanie Taylor · 08/11/2017 at 5:43 pm

    Hi Melissa, I am glad you found this article interesting and helpful. I know what you mean about IBS as I have suffered from it for a long time. It is such a hard thing to deal with and every body is different. It is one of the main reasons I researched in depth this subject as I wanted to help myself. The problem with this ‘leaky gut syndrome’ is that even though there is lots of information and research about it now coming in from all angles, many doctors don’t know or have official guidelines of how to treat it or even understand it (this is what I am led to believe anyway), so they may not be too helpful to you.

    I have actually found that since going vegan, which I have been for 9 months, it has virtually cleared up my IBS, so in my mind I can only think that eating animal hormones, which would have put my own hormones out of balance may have vastly contributed to it. As for your sleep, you should probably ask your doctor first before taking these supplements, especially if you have epilepsy as there may be contraindications. But if not, then go ahead and try them, they may help you all round with all of your issues. Good luck and I would love to know how you get on.

Dr. Doug · 11/11/2017 at 3:57 am

Is there a difference between taking L-Glutamine in a protein powder supplement to build muscle and taking it in a capsule? I was amazed to see how much work this one amino acid did. I’ve heard of it before but its not often that you get a full picture of all the functions L-Glutamine actually does in the body. Are there foods that you would recommend as well?

    Stefanie Taylor · 11/11/2017 at 3:57 am

    Hi there, yes L- Glutamine is a great little amino acid. I am taking it myself in powder from at the moment and it has really made a difference to my IBS. As for which form to take, it it probably depends on really what you prefer, the powder has a taste to it, which isn’t unpleasant but kind of lingers in your mouth. As with everything, always make sure you but from reputable brands, otherwise you may end up with a product full of fillers and preservatives. Yuck!

    There are lots of recommendations for diet, especially if you are eating for a fitness regime or just general healthy eating. My rule of thumb is always eat whole foods i.e. wholegrains, fruits, vegetables, pulses, nuts, seeds, lean meat (if you are not a veggie like me) and try to eat most veggies, fruits, nuts and seeds in as raw a state as possible to be sure you don’t damage all those nutrients and live enzymes. Please check out my plant proteins foods list for more information. Best Plant Based Protein Foods List

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